79, estrogen use a risk factor for heart disease among some younger postmenopausal women. Estrogen-alone arm of the study involved women who had previously undergone a hysterectomy Half of the women were given a form of estrogen known as conjugated equine estrogens, while the other half received a placebo. In 2004 in 2004, a year before the planned conclusion, because of concerns that estrogen , the risk of stroke and blood clots increased without benefit in terms of heart disease.
However, said Stefanick the study data not related to the timing hypothesis because only younger women were studied, so we do not know whether coronary calcium was higher or lower allocated in older women estrogen vs. Placebo. Furthermore, without a baseline computed, there is no data about changes over time. . (more…)