The results from both analyzes show that eEF1A2 moderately to highly expressed in two thirds of malignant tumor cells, whereas the protein only barely normal breast cells is expressed, the expression of eEF1A2 is up to 30-fold higher in tumor cells than in normal cells. Breast tumors.nificant overexpression in tumor cells with the estrogen receptor and in ER-negative tumor cells: 18 percent of the ER – negative tumors showed slight expression eEF1A2, whereas 63 percent of the ER-positive tumors showed significant expression the protein.. Sources: Duke University Medical Center,Written by: Catharine Paddock, The tissue – specific elongation factor eEF1A2 might be an oncoprotein in breast cancer involved a translation factor ‘ protein could be overexpressed in breast cancer cells oncoprotein oncoprotein research in the open access journal BMC Cancer published that eEF1A2 that and usually only in muscle cells.
They could then selctively stimulate the bone-forming mechanism of the PTH receptor in the bone-resorbing mechanism by switching off the G-protein – signals using an analog of PTH PTH called beta ARR .
New Way Of growing bones could help new drugs for osteoporosis fightU.S. Researchers have for open a new way of growing bones, which could open the door to development of new drugs, cellular to osteoporosis and other degenerative bone diseases by direct interception to fight processes discovered that. Control the formation and distribution of the bone in the body.Ahern et al 2009 J. Gen. Physiol.1085/jgp.200910260 Olcese, Gen. Physiol doi: 10.1085/jgp.200910353. Of improvement in the child and maternal mortality on interventions prior a woman becomes pregnant, according to officials of the March of Dimes, the U.S. Centers for Disease Control and Prevention – unprejudiced maintenance critical to the improve maternal and child mortality, healthcare and others expert.
Gene Usher In jumping Time For slowly inactivationThe December 2009 issue of the Journal of General Physiology containing an article by Christopher Ahern and colleague explored which pore mutant effects of at Shaker and other K+ channels with in vivo nonsense suppression technology.
Almost a third of of the Article have by March of Dimes professionals as co-author. The March of Dimes work in order to improve the health of babies by preventing birth defect premature birth and infant mortality rates. For more information.