5 years or until therapy was halted owing to side effects or laboratory abnormalities. If adverse events occurred that were considered to be related to linezolid, a decrease in the dose or a rechallenge at a dose of 300 mg each day was allowed after a restricted drug holiday . Linezolid was administered by means of directly observed therapy during hospitalization. The study personnel monitored outpatient adherence through videophone or telephone every weekday and in addition performed pill counts regular monthly. Patients had been treated for at least 1. 5 years after sputum-culture transformation and were followed for yet another 12 months after completing the procedure. Blood was gathered for pharmacokinetic evaluation22 of linezolid at both dosages.Nichol Thomson and Donna Albertson, Ph.D., formerly at MRC Laboratory of Molecular Biology in Cambridge, England, also contributed to the paper. Â.
PRESS RELEASE FDA’s Action to Eliminate Trans Fat CAN HELP Prevent Cardiovascular Disease and Save American Lives Statement due to:Steven J. Stack, M.D., President, American Medical Association The American Medical Association commends the U.S. Meals and Medication Administration because of its decision today to remove partially hydrogenated oils, the primary dietary source of artificialtransfat in processed foods, from all U.S.