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Mice Of GBA2: A contraceptive for male miceAlthough previously thought that a protein known important for bile acid metabolism as GBA2, shows a new study in the November issue of the Journal of Clinical Investigation that in mice GBA2 is for for male fertility. This study may explain the contraceptive effect in mice, a treatment for people without the associated protein GBA1 and could lead to the development of a new male contraceptive.
Individuals lacking the GBA2 related protein GBA1 suffer Gaucher disease and a treatment for this disease has been shown to reduce fertility in mice. This study, which identifying a crucial role in male fertility for GBA2 might help explain, effect on fertility effect on fertility of this treatment for Gaucher disease, and as Martin Matzuk and colleagues in an accompanying commentary, perhaps to help the development of a nonhormonal male pill..Phenomenon scientists researchers the Max Planck Institute for Molecular Genetics in Berlin. Scientists pushed mutations in the mitochondrial the genome of iPS cells. Because such genetic mutations can lead diseases, should said cells for such mutations are testing tested be used for clinical applications.. Induced pluripotent stem really talented multi-tasker. You can replicate most all types of cells and thus offer a great hope in the battle against diseases including Alzheimer and Parkinson’s.
One reason research group recently discovered that mitochondria rejuvenated in the wake of reprogramming of. In collaboration with Next Generation Sequencing research team Bernd Timmermann Adjaye has show team of that in mitochondrial mutations in the mitochondrial genome of all reprogrammed cells, who were not there in the original cells successful. The amount to mutations varied considerably between different studied iPS cells. Changes changes comprising include large area rearrangement but rather modifications to of single letters of the genetic code.